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Journal of the American Psychiatric Nurses Association, Vol. 5, No. 2, S2-S8 (1999)
DOI: 10.1177/107839039900500210
© 1999 American Psychiatric Nurses Association

The Relationship Between Medication Noncompliance and Cognitive Function in Patients With Schizophrenia

Kathleen S. Jarboe, APRN, CNS, MSN

Department of Psychiatry & Behavioral Sciences, Emory University School of Medicine, 1701 Uppergate Dr., #409, Atlanta, GA 30322

Sarah K. Schwartz, MSW

Department of Psychiatry & Behavioral Sciences at Emory University School of Medicine in Atlanta, Georgia

BACKGROUND:The relatively high rate of medication noncompliance in patients with schizophrenia may be in part the result of cognitive impairments frequently associated with the disorder.

OBJECTIVE: The purpose of this study was to determine whether baseline performance on specific neurocognitive tests predicts a patient's level of medication compliance. The question of whether improvement on these same tests after 3 months of antipsychotic treatment would correlate with medication compliance was also examined in this study.

DESCRIPTVE CORRELATIONAL DESIGN: Patients' medication compliance (on a percentage basis) was correlated with their baseline and 3-month posttreatment scores on four neurocognitive tests.

RESULTS: A statistically significant relationship exists between medication compliance and patients'performance on tests of attention and immediate visual recall

CONCLUSION: The results of this study support the implementation of interventions that ameliorate specific neurocognitive deficits that, in turn may facilitate improved medication compliance.


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